1990

1. Hirose, M., Masuda, A., Hasegawa, R., Wada, S., Ito, N.: Regression of butylated hydroxyanisole (BHA)-induced hyperplasia but not dysplasia in the forestomach of hamsters. Carcinogenesis, 11: 239-244, 1990.

2. Shibata, MA., Hasegawa, R., Kurata, Y., Yamada, M., Tamano, S., Fukushima, S.: Bladder epithelial hyperplasia in F344 rats after intravesical instillation of the antitumor chemotherapeutic agents Adriamycin and mitomycin C. Cancer Lett, 49: 41-49, 1990.

3. Mutai, M., Tatematsu, M., Aoki, T., Wada, S., Ito, N.: Modulatory interaction between initial clofibrate treatment and subsequent administration of 2-acetylaminofluorene or sodium phenobarbital on glutathione S-transferase positive lesion development. Cancer Lett, 49: 127-132, 1990.

4. Mori, S., Murai, T., Takeuchi, Y., Toyama, M., Makino, S., Konishi, T., Hayashi, Y., Kurata, Y., Fukushima, S.: Dose response of N-butyl-N-(4-hydroxybutyl)nitrosamine on urinary bladder carcinogenesis in mutant ODS rats lacking L-ascorbic acid synthesizing ability. Cancer Lett, 49: 139-145, 1990.

5. Shibata, MA., Yamada, M., Hirose, M., Asakawa, E., Tatematsu, M., Ito, N.: Early proliferative responses of forestomach and glandular stomach of rats treated with five different phenolic antioxidants. Carcinogenesis, 11: 425-429, 1990.

6. Hagiwara, A., Tanaka, H., Kurata, Y., Kato, T., Tsuda, H., Ito, N.: Lack of hepatotoxicity or promotion of enzyme-altered liver foci development in rats treated with harman or norharman. J Toxicol Environ Health, 29: 211-218, 1990.

7. Hirose, M., Fukushima, S., Shirai, T., Hasegawa, R., Kato, T., Tanaka, H., Asakawa, E., Ito, N.: Stomach carcinogenicity of caffeic acid, sesamol and catechol in rats and mice. Jpn J Cancer Res, 81: 207-212, 1990.

8. Shirai, T., Nakamura, A., Fukushima, S., Wang, CY., Yamada, H., Ito, N.: Selective induction of prostate carcinomas in F344 rats treated with intraperitoneal injections of N-hydroxy-3,2′-dimethyl-4-aminobiphenyl. Jpn J Cancer Res, 81:320-323, 1990.

9. Tsuda, H., Takahashi, S., Yamaguchi, S., Ozaki, K., Ito, N.: Comparison of initiation potential of 2-amino-3-methylimidazo[4,5-f]quinoline and 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline in an in vivo carcinogen bioassay system. Carcinogenesis, 11: 549-552, 1990.

10. Ogiso, T., Tatematsu, M., Tamano, S., Hasegawa, R., Ito, N.: Correlation between medium-term liver bioassay system data and results of long-term testing in rats. Carcinogenesis, 11: 561-566, 1990.

11. Shirai, T., Nakamura, A., Fukushima, S., Tada, M., Morita, T., Ito, N.: Immunohistochemical demonstration of carcinogen-DNA adducts in target and non-target tissues of rats given a prostate carcinogen, 3,2′-dimethyl-4-aminobiphenyl. Carcinogenesis, 11: 653-657, 1990.

12. Hirose, M., Masuda, A., Ito, N., Kamano, K., Okuyama, H.: Effects of dietary perilla oil, soybean oil and safflower oil on 7,12-dimethylbenz[a]anthracene (DMBA) and 1,2-dimethylhydrazine (DMH)-induced mammary gland and colon carcinogenesis in female SD rats. Carcinogenesis, 11: 731-735, 1990.

13. Shirai, T., Nakamura, A., Fukushima, S., Yamamoto, A., Tada, M., Ito, N.: Different carcinogenic responses in a variety of organs, including the prostate, of five different rat strains given 3,2′-dimethyl-4-aminobiphenyl. Carcinogenesis, 11: 793-797, 1990.

14. Hasegawa, R., Takahashi, S., Asamoto, M., Shirai, T., Fukushima, S.: Species differences in sodium o-phenylphenate induction of urinary bladder lesions. Cancer Lett, 50: 87-91, 1990.

15. Asamoto, M., Hasegawa, R., Masuko, T., Hashimoto, Y., Ueda, K., Ohtaguro, K., Sasaki, S., Washida, H., Fukushima, S.: Immunohistochemical analysis of c-erbB-2 oncogene product and epidermal growth factor receptor expression in human urinary bladder carcinomas. Acta Pathol Jpn, 40: 322-326, 1990.

16. Shibata, MA., Hirose, M., Yamada, M., Tatematsu, M., Uwagawa, S., Ito, N.: Epithelial cell proliferation in rat forestomach and glandular stomach mucosa induced by catechol and analogous dihydroxybenzenes. Carcinogenesis, 11: 997-1000, 1990.

17. Shibata, MA., Fukushima, S., Takahashi, S., Hasegawa, R., Ito, N.: Enhancing effects of sodium phenobarbital and N,N-dibutylnitrosamine on tumor development in a rat wide-spectrum organ carcinogenesis model. Carcinogenesis, 11: 1027-1031, 1990.

18. Hagiwara, A., Kurata, Y., Tamano, S.: Ectopic intestinal glands in the forestomach of a F344 rat. Vet Pathol, 27: 201-203, 1990.

19. Tatematsu, M., Ichinose, M., Miki, K., Hasegawa, R., Kato, T., Ito, N.: Gastric and intestinal phenotypic expression of human stomach cancers as revealed by pepsinogen immunohistochemistry and mucin histochemistry. Acta Pathol Jpn, 40: 494-504,1990.

20. Masui, T., Asamoto, M., Hasegawa, R., Kagawa, M., Fukushima, S.: Effects of monosodium succinate, disodium succinate, and succinic acid on urinary bladder carcinogenesis in N-butyl-N-(4-hydroxybutyl)- nitrosamine-initiated, unilaterally ureter-ligated rats. J Toxicol Pathol, 3: 105-110, 1990.

21. Cova, L., Wild, CP., Mehrotra, R., Turusov, V., Shirai, T., Lambert, V., Jacquet, C., Tomatis, L., Trepo, C., Montesano, R.: Contribution of aflatoxin B1 and hepatitis B virus infection in the induction of liver tumors in ducks. Cancer Res, 50: 2156-2163, 1990.

22. Fukushima, S., Uwagawa, S., Shirai, T., Hasegawa, R., Ogawa, K.: Synergism by sodium L-ascorbate but inhibition by L-ascorbic acid for sodium saccharin promotion of rat two-stage bladder carcinogenesis. Cancer Res, 50: 4195-4198, 1990.

23. Kurata, Y., Fukushima, S., Hasegawa, R., Hirose, M., Shibata, MA., Shirai, T., Ito, N.: Structure-activity relations in promotion of rat urinary bladder carcinogenesis by phenolic antioxidants. Jpn J Cancer Res, 81: 754-759, 1990.

24. Tatematsu, M., Katsuyama, T., Furihata, C., Fukushima, S., Shirai, T., Kato, T., Ito, N.: Cellular differentiation and histogenesis of rat glandular stomach cancers. Jpn J Cancer Res, 81: 760-767, 1990.

25. Hagiwara, A., Tamano, S., Shibata, MA., Arai, M., Tsuda, H.: Lack of modifying effects of p-phenylenediamine on induction of γ-glutamyl transpeptidase-positive foci in a medium-term bioassay system using F344 rats. Toxicol Lett, 52: 261-268, 1990.

26. Hirose, M., Fukushima, S., Hasegawa, R., Kato, T., Tanaka, H., Ito, N.: Effects of sodium nitrite and catechol or 3-methoxycatechol in combination on rat stomach epithelium. Jpn J Cancer Res, 81: 857-861, 1990.

27. Hasegawa, R., Furukawa, F., Toyoda, K., Takahashi, M., Hayashi, Y., Hirose, M., Ito, N.: Inhibitory effects of antioxidants on N-bis(2-hydroxypropyl)nitrosamine-induced lung carcinogenesis in rats. Jpn J Cancer Res, 81: 871-877, 1990.

28. Nakamura, A., Shirai, T., Ogawa, K., Wada, S., Fujimoto, NA., Ito, A., Ito, N.: Promoting action of prolactin released from a grafted transplantable pituitary tumor (MtT/F84) on rat prostate carcinogenesis. Cancer Lett, 53: 151-157, 1990.

29. Hagiwara, A., Yamada, M., Hasegawa, R., Fukushima, S., Ito, N.: Lack of enhancing effects of fenvalerate and esfenvalerate on induction of preneoplastic glutathione S-transferase placental form positive liver cell foci in rats. Cancer Lett, 54: 67-73, 1990.

30. Wada, S., Hirose, M., Takahashi, S., Okazaki, S., Ito, N.: Para-methoxyphenol strongly stimulates cell proliferation in the rat forestomach but is not a promoter of rat forestomach carcinogenesis. Carcinogenesis, 11: 1891-1894, 1990.

31. Asamoto, M., Shichino, Y., Tsuda, H., Ito, N.: Inhibition of rat hepatic glutathione S-transferase placental form positive foci development by concomitant administration of antioxidants to carcinogen-treated rats. Cancer Lett, 55: 25-29, 1990.

32. Imaida, K., Hirose, M., Yamaguchi, S., Takahashi, S., Ito, N.: Effects of naturally occurring antioxidants on combined 1,2-dimethylhydrazine- and 1-methyl-1-nitrosourea-initiated carcinogenesis is F344 male rats. Cancer Lett, 55: 53-59, 1990.

33. Tamano, S., Kurata, Y., Kawabe, M., Yamamoto, A., Hagiwara, A., Cabral, R., Ito, N.: Carcinogenicity of captafol in F344 /DuCrj rats. Jpn J Cancer Res, 81: 1222-1231, 1990.

34. Hagiwara, A., Tamano, S., Ogiso, T., Asakawa, E., Fukushima, S.: Promoting effect of the peroxisome proliferator, clofibrate, but not di(2-ethylhexyl)phthalate, on urinary bladder carcinogenesis in F344 rats initiated by N-butyl-N-(4-hydroxybutyl)nitrosamine. Jpn J Cancer Res, 81: 1232-1238, 1990.

35. Kurata, Y., Fukushima, S., Hagiwara, A., Ito, H., Ogawa, K., Ito, N.: Carcinogenicity study of methyl hesperidin in B6C3F1 mice. Fd Chem Toxicol, 28: 613-618, 1990.

36. Ichinose, M., Miki, K., Tatematsu, M., Furihata, C., Matsushima, M., Ichihara, Y., Tanji, M., Konishi, T., Obara, M., Inoue, H., Kurokawa, K., Takahashi, T., Kageyama, T., Takahashi, K.: Hydrocortisone-induced enhancement of expression and changes in methylation of pepsinogen genes in stomach mucosa of the developing rat. Biochem Biophys Res Comm, 172: 1086-1093, 1990.

37. Yamaguchi, S., Tatematsu, M., Furihata, C., Takaba, K., Ito, N.: Effects of bile acids on development of pepsinogen-altered pyloric glands in rats. Cancer Lett, 55: 129-134, 1990.

38. Ikawa, E., Tagawa, Y., Shirai, T., Hirose, M., Fukushima, S.: Induction of preneoplastic lesions by sequential treatment of rats with three carcinogens: N-butyl-N-(4-hydroxybutyl)nitrosamine, 7,12-dimethylbenz(a)anthracene, and N-methyl-N-nitro-N-nitrosoguanidine. J Toxicol Pathol, 4: 63-66, 1990.

39. Moore, MA., Thamavit, W., Tiwawech, D., Ito, N.: Absence of any enhancing effect of concomitant administration of 3-aminobenzamide on propylnitrosamine induction of tumour development in F344 rats and Syrian golden hamsters. Thai Cancer J, 16: 79-83, 1990.

40. Okamura, T., Tsugaya, M., Watase, H., Ueda, K., Hasegawa, R., Fukushima, S., Ohtaguro, K.: Various urinary properties in bladder tumor patients. Jpn J Clin Oncol, 20: 154-158, 1990.

41. Ito, N., Hirose, M., Hagiwara, A., Takahashi, S.: Carcinogenicity and modification of carcinogenic response by antioxidants. In: Kuroda, Y., Shankel, DM. & Waters, MD. (eds.) Antimutagenesis and Anticarcinogenesis Mechanisms II, pp183-194. Plenum Publishing Co., 1990.

42. Ito, N., Shirai, T., Thamavit, W., Pairojkul, C.: Opisthorchis viverrini and liver tumors in northeastern Thailand. In: Sasaki, R. & Aoki, K. (eds.) Epidermiology & Prevention of Cancer, pp60-65. Univ. Nagoya Press, Nagoya, 1990.

43. Fukushima, S., Shibata, MA., Shirai, T., Hasegawa, R.: Cancer and vitamin C. In: Fujita, T., Fukase, M. & Konishi, T. (eds.) Vitamin C and the Scurvy-Prone ODS Rat, pp211-222. Elsevier Science Publishers B.V. (Biomedical Division), 1990.

44. Mori, S., Murai, T., Toyama, M., Takeuchi, Y., Makino, S., Konishi, T., Hayashi, Y., Kurata, Y., Fukushima, S.: Urinary bladder carcinogenesis by N-butyl-N-(4-hydroxybutyl)nitrosamine in ODS rats. In: Fujita, T., Fukase, M. & Konishi, T. (eds.) Vitamin C and the Scurvy-Prone ODS Rat, pp223-235. Elsevier Science Publishers B.V. (Biomedical Division), 1990.

45. Tsuda, H., Asamoto, M., Kagawa, M., de Camargo, JLV., Ito, N., Nagase, S.: Strain differences in susceptibility to 2-acetylaminofluorene and phenobarbital promotion of rat hepatocarcinogenesis in a medium-term bioassay system. In: Fujita, T., Fukase, M. & Konishi, T. (eds.) Vitamin C and the Scurvy-Prone ODS Rat, pp237-245. Elsevier Science Publishers B.V. (Biomedical Division), 1990.

46. Tada, M., Kojima, M., Shirai, T., Ito, N., Morita, T.: Immunological detection and quantitation of carcinogen-DNA adducts. In: Vanderlaan, M. et al. (eds.) Immunoassays for Trace Chemical Analysis, Vol. 451, pp246-256. American Chemical Society, Washington, DC, 1990.